“We’ve done a couple other premieres of Sartor’s work,” Conrad said. It should be a really fun piece.”Ĭonrad said the “Scarab!” is a world premiere by composer David Sartor, who lives in Nashville, Tenn. ‘I’m interested in seeing how that goes together. “There is a piece about a beetle called ‘Scarab!’ with flute, bassoon and harp,” said Gallant, an Indianapolis resident who has been with IWS for 20 years. There also is a piece by Reynaldo Hahn called “Le Bal de Beatrice d’Este.” “It’s incidental music that was used from one of his plays,” Gallant said. Gallant will perform on Stephen Sondheim’s suite from “Invitation to a March.” The guest conductor is flute player Laura Recendez. IWS Music Director Charles Conrad will conduct most of the concert. March 4 at the Studio Theater at the Center for the Performing Arts in Carmel. Indiana Wind Symphony will feature its harp soloist Melissa Gallant at 7:30 p.m. They also showed low technical variability of single cell sequencing analysis among various clinical centers demonstrating the feasibility of using single cell sequencing in multicenter trials in the future.Indiana Wind Symphony’s upcoming concert is aptly named “Sound the Harp.” O Enriched communication of BAFF and CCL signaling pathways in T and myeloid cells. O Rnrichment of IFN-ɣ and IFN-δ downstream targets in myeloid cells O Decreased expression of cytolytic markers The authors characterized the immune microenvironment modifications associated with rapid progressors among multiple myeloma patients such as: This recent study shows how #singlecell #sequencing can leverage new findings about the #tumormicroenvironment in multiple myeloma in the context of multicenter clinical trials: It’s an exciting time for #multiplemyeloma research. #MultipleMyeloma #cartcelltherapy #NovelApproach #ClinicalTrials #Treatment #CancerResearch #Oncology #MedicalAdvancements This comprehensive review highlights the development and outcomes of CAR T-cell therapy in MM, the limitations and toxicities associated with the therapy, and the strategies being pursued to overcome therapeutic challenges in the pursuit of a cure for MM.Īs a rapidly evolving field, CAR T-cell therapy in MM represents a crucial area of study for oncologists and researchers alike.īy highlighting the current state of the field and areas for further investigation, this review provides valuable insights into the future of CAR T-cell therapy in the treatment of MM. In light of this unmet medical need, the development of chimeric antigen receptor (CAR) T-cell therapy has emerged as a promising approach for the treatment of relapsed, refractory MM (RRMM).ĬAR T-cell therapy involves the genetic modification of cellular therapies, which have shown significant efficacy in achieving deep and durable remissions in other B-cell malignancies.Įarly studies of CAR T-cell therapy in RRMM have demonstrated remarkable response rates, however, long-term durability remains an area of ongoing research. Multiple myeloma (MM) is a hematologic malignancy characterized by the clonal proliferation of transformed plasma cells.ĭespite significant progress in MM treatment, a cure remains elusive for the majority of patients, especially those with triple-class refractory MM who have developed resistance to immunomodulatory agents, proteasome inhibitors, and monoclonal antibodies. Shane Swatts Miguel López de Silanes Gómez Carmelo Chines Fabrizio Chines Benoit COLLET Nick Atkins Rachna Murthy Jonathan Roos Alessandro Moroni Yvonne Hernández González Rick Good Samer Hamada Dr. FAAO Christopher Starr Benjamin Sullivan John Gelles Yang Liu Sabrina Zappia Dr. #TFOSLifestyle #eyesarethestory #ocularsurfacedisease #dryeye #eyecare #cosmetics #scienceofeyes #teamwork #optocosmetics Bridgitte Shen Lee, OD, FAAO, FBCLA, FEAOO, Dipl ABO Leslie O'Dell, O.D. Look forward to sharing more of “The Story” around the world! Key takeaway: Education is paramount (and too many female ophthalmologists & patients in the Middle East apply eyeliner to their waterline!) Lazreg Sihem from Algeria and discussed how we can better educate clinicians and patients worldwide on eye-safe cosmetics. And, very proud of Dad who gave the Keynote and received an award and recognition for his global achievements. Great honor to be on stage with my father, David Sullivan, and Stefano Barabino from Milano. Whirlwind visit to Abu Dhabi to present at the 20th Emirates Society of Ophthalmology Conference - about how cosmetics impact the ocular surface.
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